IMPACT Collaboratory 2025 Career Development Award Program

The National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s Disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory (U54AG063546) is now accepting applications for the 2025 Career Development Award (CDA) Program. These CDAs support the development of MD, PhD, or equivalent researchers who seek careers conducting embedded pragmatic clinical trials (ePCTs) for people living with AD/ADRD and their care partners.

This mechanism will fund research projects that are preparatory to conducting a future ePCT such as secondary data analysis, intervention development or the development of outcomes to be used in ePCTs. The proposed CDA project cannot include a clinical trial (including pilot trials; see NIH definition of a clinical trial).

The IMPACT Collaboratory will fund up to two awards. Each award will provide $240,000 in total direct costs over two years. Facilities & administrative (indirect) costs may not exceed 8% of total direct costs. Each year, at least $20,000 in direct costs must be allocated for research-related expenses, such as travel, publication costs, analytic, technical or project support, data acquisition, certified translations, or other activities directly related to the goals of the award. Awardees are required to devote a minimum of 50% effort toward the goals of the award.

Read the full RFA here.

Important Dates

Informational Webinar

An optional informational webinar will be hosted to provide investigators with an overview of application details and an opportunity to ask questions.

 December 3, 2025 @ 12:00 PM ET: Register here.

Applications are due January 15, 2026 @ 11:59pm ET

Click here to view full RFA

Questions? Please contact, Elaine Bergman, IMPACT Communications Lead