NIH Stage Model in Action

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The National Institutes of Health Stage Model for Behavioral Development is designed to produce highly potent and maximally implementable behavioral interventions that improve health and well-being. Composed of six individual stages, the Model emphasizes scientific and practical value in determining the mechanism of actions of interventions; promotes the creation of a cumulative, progressive field; and assists in the identification of behavior-change principles that can be imparted to those responsible for delivering interventions. Its emphasis on mechanisms facilitates the operationalization of personalized interventions tailored to different characteristics of individuals, couples, and families for a broad range of behaviors across settings.

Translational Research 

The National Center for Advancing Translational Sciences describes translation science as "the process of turning observations in the laboratory, clinic, and community into interventions that improve the health of individuals and the public." 


The translational science spectrum represents the various levels of interaction between each stage of research:

  • Basic research (exploring basic functions of biology, disease, or behavior)

  • Pre-clinical research (connecting the basic science of disease with human medicine)

  • Clinical research (gathering data to better understand disease and test technologies and interventions)

  • Clinical implementation (adopting interventions that have been demonstrated to be useful in a research environment)

  • Public health (studying health outcomes at the population level to determine the effects of diseases and efforts to prevent, diagnose, and treat them)


The Roybal Center resources focus on translational research at stages 0 through IV of the NIH Stage Model. The program thereby aims to create effective, principle-driven interventions that improve the emotional and physical well-being of mid-life and older adults while enhancing the capacity of institutions to adapt to societal aging.