NIH Common Fund Complement-ARIE Reduction to Practice Prize
- Roybal Coordinating Center
- Oct 1
- 1 min read
The NIH Common Fund has teamed up with NASA’s Tournament Lab to launch the Reduction to Practice Prize, a competition that invites innovative New Approach Methodologies (NAMs) solutions from teams who can successfully demonstrate implementation of integrated human-based solutions in a practical and usable form within a 3-year period.
The goal of this challenge is to accelerate and catalyze near-ready combinatorial NAMs to a practicable form that can be submitted to the Complement-ARIE Validation and Qualification Network (VQN), managed by the Foundation for NIH.
This challenge has three phases:
Phase 1: Proof of Concept and Feasibility Studies: Phase 1 submissions will include a clear description of intended use for the proposed combinatorial NAM solution.
Phase 2: Prototype Development and Milestone Achievements: Phase 2 will be milestone-driven. Solvers will demonstrate:
Milestone 1: Progress toward meeting the initial performance and testing requirements of the NAMs platform in a specific context-of-use and successful construction and scaling of the NAMs platform according to fit-for-purpose needs.
Milestone 2: Progress toward internal validation of the NAMs platform using reference standards/compounds/agents and demonstrated within-laboratory reproducibility of results.
Phase 3: Prototype Delivery for Validation and Qualification: Top-scoring submissions will be delivered to the VQN for independent validation and qualification.
The total cash prize purse for this competition is $7,000,000 to be shared among winners.
Submit your ideas by Mar 01, 2026 at 11:59PM ET
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