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Notice of Funding Opportunity: AD/ADRD Exposome Research Coordinating Center

RFA-AG-24-011 - Research Coordinating Center on the Exposome and Alzheimer's Disease (AD) and AD-Related Dementias (ADRD): Elucidating the Role of Social and Behavioral Determinants of Health in AD/ADRD Etiology and Disparities (U24 Clinical Trial Not Allowed)

The NOFO invites applications that propose to establish a national coordinating center that will serve as a centralized hub for accessing, harmonizing, linking, and sharing environmental contextual data and individual exposure data with NIA/NIH-funded projects. The aim of this initiative is to foster collaboration and accelerate life course research on the social, behavioral, psychological, and economic exposures that shape Alzheimer’s disease (AD) and AD-related dementias (ADRD) outcomes and inequities.

Applications to establish the AD/ADRD Exposome Coordinating Center must identify five to seven social, behavioral, psychological, and economic exposome domains relevant to AD/ADRD, and describe activities related to the domains that will achieve the following objectives of this NOFO:

  1. To develop an organizational and governance structure to support the administration, innovation, and dissemination functions of the center.

  2. To propose activities to establish guidance and practices for the use and harmonization of exposure data across NIA-supported infrastructure projects, as well as other longitudinal studies of aging. Additionally, to propose and support activities for the development of innovative and novel exposure measures and data.

  3. To disseminate resources and products developed by the center to the broader AD/ADRD research community to expand the use of social and behavioral data and harmonized measures in a wide range of studies.

For Innovation and Dissemination activities throughout the course of this initiative, applicants must engage with a wide range of NIA-supported AD/ADRD infrastructure projects, such as the centers in the NIA Research Centers Collaborative Network (RCCN), and with other NIA-funded programs and centers.

Applications are due September 27, 2023.

A technical webinar will be held on April 20, 2023 at 2:00 pm Eastern Time. NOT-AG-23-010 - Notice of Pre-Application Webinar for RFA-AG-24-011 - Research Coordinating Center on the Exposome and AD/ADRD: Elucidating the Role of Social and Behavioral Determinants of Health in AD/ADRD Etiology and Disparities (U24 Clinical Trial Not Allowed).







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