Request for Applications for NIA IMPACT's Pilot Grants Program
- Roybal Coordinating Center
- Oct 16
- 1 min read
The IMPACT Collaboratory is pleased to announce a Request for Applications for the 2025 Pilot Grants Program. The National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory (U54AG063546) was established in 2019 to build the nation’s capacity to conduct embedded pragmatic clinical trials (ePCTs) of non-pharmacological interventions within health care systems to improve the care of people living with dementia (PLWD) and their care partners.
The IMPACT Collaboratory will fund up to three awards for pilot pragmatic clinical trials (ePCTs) that that are designed to demonstrate the feasibility and inform the design of a future full-scale ePCT (Stage IV effectiveness based on the NIH Stage Model) to evaluate non-pharmacological interventions embedded in health care system(s) for PLWD and their care partners.
Awards are for 18 months, up to $300,000 (total direct costs), and are non-renewable. Read the full RFA here.
Important Dates
Informational Webinar
An optional informational webinar will be hosted to provide investigators with an overview of application details and an opportunity to ask questions.
Thursday, October 23, 2025, at 1:00pm ET: Register here.
Letters of Intent (LOI) – Required
Interested applicants are required to submit an LOI. LOIs are accepted on a rolling basis through: Thursday, November 6, 2025, at 11:59pm ET
Full Proposals (By invitation only)
Applications selected for further consideration will be invited to submit a full proposal due:
Thursday, February 12, 2026, at 11:59pm ET.