Requesting Applications for Career Development Awards

The National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer's Disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory is now accepting applications for the Career Development Award (CDA). These CDAs support the development of MD, PhD, or equivalent researchers who seek careers conducting embedded pragmatic clinical trials (ePCTs) for people living with AD/ADRD and their care partners.

The IMPACT Collaboratory will fund up to two 2-year CDAs, prioritizing applications that address dementia care for people of all backgrounds and promote health equity. Each award will provide up to $220,000 in direct costs over two years with an indirect cost rate capped at 8%. Awardees are required to devote a minimum of 75% effort toward the goals of the award. Eligible applicants include MD, PhD, or equivalent researchers who seek careers conducting ePCTs for people living with AD/ADRD and their care partners. Applicants are typically within 7 years of their post-doctoral training program at the time of application. Exceptions will be made in this round of funding for investigators with more than 7 years who can demonstrate evidence of changing their career path to pursue research on ePCTs among PLWD. Such applicants must request prior approval. Applications are due Thursday, September 15, 2022 by 5pm ET. An informational webinar will be hosted on Wednesday, June 29, 2022 at 2:00 PM ET to provide investigators with an overview of application details. Investigators will have the opportunity to ask questions. Use this link for required pre-registration.

NIA IMPACT Funding Opportunities

​Pilot Grants RFA Total Direct Costs up to $175,000 Award Duration 12 months Informational Webinar August 30, 2022 @ 3pm ET. Register here. Letters of Intent Due September 15, 2022 @ 5pm ET Full Proposals Due January 20, 2023 @ 5pm ET

​Pilot Grants RFA Total Direct Costs up to $175,000 Award Duration 12 months Informational Webinar August 30, 2022 @ 3pm ET. Register here. Letters of Intent Due September 15, 2022 @ 5pm ET Full Proposals Due January 20, 2023 @ 5pm ET

Pilot Grants Program IMPACT will fund up to five 1-year awards for pilot pragmatic clinical trials (ePCTs) that test non-pharmacological interventions embedded in health care system(s) for people living with Alzheimer’s Disease (AD) and AD-related dementias (ADRD) and their care partners. The goal of these pilot studies is to generate the preliminary data necessary to design and conduct a future full-scale Stage IV effectiveness ePCT (based on the NIH Stage Model) funded through other grant mechanisms. This grant cycle will prioritize applications for non-pharmacological interventions that aim to:

• Reduce inequities in health care

• Reduce potentially inappropriate medications through de-prescribing

• Improve care in the emergency department

Learn more about previous Pilot Grant Awardees here. If you have questions about the Pilot Grant Program please visit the Frequently Asked Questions webpage or email IMPACTcollaboratory@hsl.harvard.edu. ​ Demonstration Projects Program IMPACT will fund up to two 18-month Demonstration Projects designed as full-scale, Stage IV effectiveness ePCTs (based on the NIH Stage Model) that test, measure and evaluate the effect of a care delivery intervention program in health care systems for people living with AD/ADRD and their care partners. The goal of these Demonstration Projects is to generate evidence on effective care delivery practices that can be expanded and/or implemented in other systems. Under this mechanism, the interventions must be linked to the needs of the health care system. Suitable intervention typically encompass relatively simple system changes or direct patient outreach, or successfully piloted programs ready for testing at scale. Demonstration Projects allow health care systems and investigators to gain real-world experience integrating pragmatic non-pharmacological interventions into usual clinical workflow and health care delivery practices in a controlled manner that provides clear information on the impact of the intervention program. Learn more about previous Demonstration Project Awardees here. If you have questions about the Demonstration Project Program, please visit the Frequently Asked Questions webpage or email IMPACTcollaboratory@hsl.harvard.edu.