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The National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s Disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory has launched a Request for Applications for the 2026 Health Care Systems Scholars Program.


The IMPACT Collaboratory will fund up to two Health Care System Scholar Awards. Each award will provide $120,000 in total direct costs for a 1-year mentored experience designed to support immersion of investigators (MD, PhD, or equivalent) within a health care system to foster durable partnerships, advance system-informed research priorities, and lay the groundwork for future embedded pragmatic clinical trials in dementia care.


Through funded, protected time embedded within a health care system, Scholars build collaborative partnerships, gain a strong understanding of system priorities, clinical workflows and data infrastructures, and co-design interventions and implementation strategies that align with real-world needs, enhancing readiness for future pilot or full-scale ePCTs.


Each scholar will complete a mentored project in collaboration with the HCS that focuses on identifying system priorities in dementia care and co-designing an intervention and implementation strategy to address those needs, preparing the partnership for an ePCT. Scholars will also participate in monthly meetings of the Health Care Systems Core, peer-learning sessions, and research-in-progress seminars. In addition, they will have opportunities to engage in the activities of the IMPACT Collaboratory, including Grand Rounds, training opportunities, and annual meetings that foster interdisciplinary exchange, professional development, and methodological advancement.


The Health Care Systems (HCS) Scholars Program supports researchers in partnering with a health care system or organization that provides care for people living with dementia or their care partners to:

1.      Build meaningful relationships with HCS staff at all levels, from frontline clinicians and direct care providers to system leaders.

2.      Develop a comprehensive understanding of the health care system, including staff-identified needs of people living with dementia and care partners, organizational priorities, clinical workflows, data infrastructure, and processes for implementing new programs.

3.      Engage HCS staff in identifying opportunities to improve and/or evaluate dementia care and enhance understanding of what it means to conduct embedded pragmatic clinical trials (ePCTs) within their setting(s).

4.      Co-develop a research proposal for an ePCT aimed at improving care for people living with dementia and care partners.


Eligible individuals include MD, PhD, or equivalent investigators – typically mid-career or approaching mid-career – with an established or developing focus on conducting ePCTs for PLWD and their care partners.  Candidates are required to apply with an identified health care system and be affiliated with an organization based in the United States (US) and be US citizens, non-citizen nationals, or permanent residents at the time of application. No research may be conducted outside of the US.



Informational Webinar

An optional informational webinar will be hosted to provide investigators with an overview of application details and an opportunity to ask questions.


Thursday, February 26 @ 12:00 PM ET: Register here.

Letters of intent are due April 2, 2026 at 8pm ET

Questions? Please contact, Elaine Bergman, IMPACT Communications Lead


Principal Investigators: Sarah Berry, MD, MPH, Marcus Institute for Aging Research, Hebrew Senior Life; Vince Mor, PhD, Brown University School of Public Health Drs. Berry and Mor were awarded a supplement to improve COVID-19 testing for underserved and vulnerable populations as part of the Rapid Acceleration of Diagnostics (RADx) initiative, the RADx Underserved Populations (RADx-UP) program. This initiative will leverage the foundation of the IMPACT Collaboratory to establish IMPACT-COVID-19 (IMPACT-C), a collaborative dedicated to developing and evaluating SARS-CoV-2 testing strategies in highly vulnerable residents and health care workers of skilled nursing facilities. IMPACT-C will assemble the organizational, administrative, and expertise components necessary to swiftly conduct a rigorous vaccine trial, when available.


Principal Investigator: Ellen McCreedy, PhD, MPH, Brown University School of Public Health

Dr. McCreedy and her team will conduct a cluster randomized embedded pragmatic clinical trial (ePCT) by leveraging electronic health records of Bluestone Physician Services to test the effectiveness of a COVID-specific, advance care planning (ACP) intervention on documentation of care preferences among assisted living community (ALC) residents with AD/ADRD from 150 ALCs in 3 states.


Principal Investigator: Lewis Lipsitz, MD, Marcus Institute for Aging Research, Hebrew SeniorLife

Dr. Lipsitz and his team will evaluate the efficacy of a Massachusetts state-funded strategy to minimize the spread of COVID-19 among older adults and their care providers within Massachusetts NHs using multiple data sources. Efficacy will be measured over the 2-month intervention period among all residents in nursing homes (NHs) across Massachusetts compared to those in Connecticut, Rhode Island, New Hampshire, and Vermont.


Principal Investigator: Joshua Chodosh, MD, MSHS, NYU Langone Health Dr. Chodosh and his team will design and pilot test an intervention that leverages the COVID-19 antibody and PCR status of residents and staff to inform staff-residents care assignments to minimize COVID-19 transmission rates. The team will conduct the study in two New York City facilities with high minority and AD/ADRD representation and compare intervention units using this strategy with those that do not.


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