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Led by expert faculty -  Dr. Linda Collins, Dr. Kate Guastaferro, and Dr. Kelly Rulison - this training is a discussion-based, synchronous course on intervention optimization that will be held online via Zoom using a “flipped classroom” approach. It is designed for intervention scientists who want to explore an innovative approach to intervention research and acquire the background and skills needed for a successful grant proposal involving MOST. Eligible applicants must hold a PhD, MD, or equivalent degree, and have completed graduate training in applied statistics through at least multiple regression. If accepted, participants will be required to complete accompanying asynchronous modules.


This course is aimed at intervention scientists working in any area—public health, education, criminal justice, and others—interested in learning about an innovative framework for conducting intervention research.

The course will show you how to use the Multiphase Optimization STrategy (MOST) to: streamline interventions by eliminating inactive components; identify the combination of components that offers the greatest effectiveness without exceeding a defined implementation budget; develop interventions for immediate scalability; look inside the “black box” to understand which intervention components work and which do not; and improve interventions programmatically over time. In this course you will relate the MOST framework to your research objectives; learn how MOST differs from the standard approach to intervention development and evaluation; learn how to complete the preparation and optimization phases of MOST; and become familiar with rigorous and highly efficient experimental designs that will enable you to examine the performance of individual intervention components. It will also cover practical issues, such as conducting an optimization trial in a field setting, and strategy for submitting a grant proposal to support intervention optimization.

This course will be held online using a “flipped classroom” combination synchronous/asynchronous approach. To prepare for each synchronous session, learners will be expected to have completed (i) asynchronous modules (currently hosted on Coursera) and (ii) an assignment applying what is learned to the learner’s own research. The assignment will be presented briefly and discussed in small breakout groups.


Completing the asynchronous modules in advance of their assigned training day is essential because very little time will be devoted to lectures during the synchronous sessions. Instead, during our time together we will focus on reinforcing what was learned in the asynchronous course by: addressing questions that arose during completion of the modules; discussing the material to relate the ideas to specific research agendas; conducting small group presentations/discussion of the assignments; and reviewing practical issues such as how to write a successful grant proposal related to intervention optimization.


The registration fee for this workshop is $750. If the cost poses a financial hardship, please complete the application and contact us directly at cadiotrainings@nyu.edu. Submit the brief application here and visit our website for more information.


Jul 10, 2025 12:00 PM ET
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Dr. David L. Roth is a Professor Emeritus of Geriatric Medicine and Biostatistics at Johns Hopkins University. He was trained as a clinical psychologist and has considerable expertise as an applied statistician, with over 40 years of experience as an NIH-funded investigator. In addition to his collaborative contributions, Dr. Roth served as a Principal Investigator on multiple R01 grants that examined the health effects (and benefits) of family caregiving using data from large national epidemiological investigations. Although Dr. Roth retired from his full-time academic position in 2024, he continues to be an active scholar and serves as a consultant on multiple funded projects, including the EMBRACE Roybal Center. He has a long history of collaboration with EMBRACE Center leaders.


This presentation will introduce investigators to key decisions that must be made when testing intervention mechanistic hypotheses with statistical mediation methods. Topics will include whether change scores or post-treatment scores should be analyzed, how baseline (pre-treatment) measures should be used as covariates, the importance of selecting mediating variables with very high reliabilities, and the availability of multiple methods for testing the statistical significance of and interpreting the magnitude of the mediated effect.

Wednesday, June 25, 2025 | 12–1 PM ET / 9–10 AM PT

mHealth, or mobile health, can play a significant role in promoting healthy aging by leveraging technology to support self-management of chronic conditions, improve physical activity, and enhance overall well-being and connection for older adults. Mobile technologies also at the forefront of personalized medicine, supporting proactive health management and can improve outcomes for various conditions.


To explore this unique intersection of cutting-edge technology and aging research, join AFAR for a free webinar tailored for professionals in the scientific and entrepreneurial communities.


Experts from the geroscience and biotech sectors not only will discuss how research and technical advances in mHealth can improve the experience of both providers and patients, but also address barriers to engaging consumers and practitioners fully in mHealth opportunities, and explore opportunities for collaboration between the academic and private sectors in this growing space


Featured Speakers:
  • Megan Huisingh-Scheetz, MD, MPH

    Associate Professor, Associate Director of the Aging Research Program, Co-Director of the Successful Aging and Frailty Evaluation Clinic, Geriatrics and Palliative Medicine,

    University of Chicago


  • Connor Landgraf

    Co-Founder and CEO, Eko Health


  • Julie Rekant, DPT, PhD

    Visiting Post-Doctoral Fellow, Department of Physical Therapy and Rehabilitation Science

    University of Maryland School of Medicine


  • Michael Snyder, PhD

    Stanford W. Ascherman Professor of Genetics;

    Director, Center for Genomics and Personalized Medicine

    Stanford University

Moderator:
  • Sergey Young

    AFAR Board Member, Co-Founder of BOLD Longevity Fund

    Author, The Science and Technology of Growing Young


Topics Include:
  • How mHealth improves patient and provider experiences

  • Barriers to widespread adoption

  • Opportunities for cross-sector collaboration


This event is ideal for researchers, entrepreneurs, and healthcare professionals interested in the intersection of technology and aging.




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